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What causes hair loss?

1. Age

As we age, the hair's growth phases (anagen phases) shorten, while the resting phases (telogen phases) last longer. This causes hair to become thinner and the scalp to become more visible. A condition known as 'kenogen' often occurs: hair follicles remain in the resting phase and do not produce new hair.

2. Chronic stress & microbiome imbalance

UV radiation, environmental pollution, and a disrupted scalp microbiome promote the formation of reactive oxygen species (ROS). These cause oxidative stress, which triggers inflammatory reactions and reduces hair follicle regeneration.

3. Hormonal changes

Hormonal changes, especially during menopause and after pregnancy, can exacerbate hair loss. This is caused by a decline in estrogen, which normally has a protective effect on the scalp and hair follicles. The resulting excess of androgens such as testosterone further damages the hair follicles.

Attention men

Androgenetic alopecia (AGA) is the most common form of hair loss. While approximately 42% of women are affected at some point in their lives, the figure for men is around 80%. The initial symptoms typically include thinning of the frontal hairline, followed by diffuse thinning in the vertex area. In addition to genetic factors, studies suggest that the scalp and gut microbiome, as well as nutrient deficiencies, can also contribute to AGA.

The 4 superstars against hair loss

Which active ingredients have a preventative effect and support hair regrowth?

1. Collagen

Studies show that collagen can inhibit the activity of the growth-inhibiting messenger TGF-β1, which is overactive in conditions such as androgenetic alopecia (AGA). Collagen also protects against oxidative stress and supports scalp regeneration, both of which can contribute to extending the growth phases (anagen phases). At the same time, collagen promotes the production of keratin, the main component of hair, and can thus lead to stronger and more resilient hair.

2. Hyaluronic acid

Hyaluronic acid maintains the moisture balance of the scalp and thus creates the basis for healthy hair follicles.

3. Saw palmetto dry extract

Saw palmetto contains phytosterols and flavonoids, which have anti-inflammatory properties and can regulate hormonal imbalances. It is therefore often used for hormonally-induced hair loss such as AGA, as it can inhibit the effects of dihydrotestosterone (DHT), a hormone that stimulates the production of the growth inhibitor TGF-β1.

4. Postbiotic bacterial strains

Postbiotically derived metabolites and cell fragments are being researched in relation to the natural balance of the gut and skin microbiome. The so-called gut-skin axis describes the connection between the gut and skin, through which signals and metabolites from the gut can influence skin health. A balanced gut microbiome often also has a positive effect on the skin—including the scalp. A healthy gut microbiome also supports the absorption of essential nutrients such as zinc and biotin, which can promote hair regeneration and encourage hair growth.

The best part: Our beauty drink combines all four superstars with additional supporting active ingredients, offering a practical all-in-one solution.



Interested? Find out here how our Beautybacs can improve your skin.

sources

Monselise A, Cohen DE, Wanser R, Shapiro J. What Ages Hair? Int J Womens Dermatol. 2017 Feb 16 3(1 Suppl):S52-S57. doi: 10.1016/j.ijwd.2017.02.010. PMID: 28492040 PMCID: PMC5419032. Rebora A, Guarrera M. Kenogen. A new phase of the hair cycle? Dermatology. 2002 205(2):108-10. doi: 10.1159/000063908. PMID: 12218222. Franceschi, C., Bonafè, M., Valensin, S., Olivieri, F., De Luca, M., Ottaviani, E., & De Benedictis, G. (2000). Inflammaging. An evolutionary perspective on immunosenescence. Annals of the New York Academy of Sciences, 908, 244-254. https://doi.org/10.1111/j.1749-6632.2000.tb06651.x Pajak J, Nowicka D, Szepietowski JC. Inflammaging and Immunosenescence as Part of Skin Aging-A Narrative Review. Int J Mol Sci. 2023 Apr 24 24(9):7784. doi: 10.3390/ijms24097784. PMID: 37175491 PMCID: PMC10178737. Price, V. H. (1999). Treatment of Hair Loss. New England Journal of Medicine, 341(13), 964-973. doi:10.1056/nejm1999092334113 Grymowicz, M., Rudnicka, E., Podfigurna, A., Napierala, P., Smolarczyk, R., Smolarczyk, K., & Meczekalski, B. (2020). Hormonal Effects on Hair Follicles. International Journal of Molecular Sciences, 21(15), 5342. https://doi.org/10.3390/ijms21155342 Kamp, E., Ashraf, M., Musbahi, E., & DeGiovanni, C. (2022). Menopause, skin and common dermatoses. Part 1: hair disorders. Clinical and experimental dermatology, 47(12), 2110-2116. https://doi.org/10.1111/ced.15327 Randall, V. A. (2008). Androgens and hair growth. Dermatologic Therapy, 21(5), 314-328. https://doi.org/10.1111/j.1529-8019.2008.00214.x

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